Hsp is characterized by the classic tetrad of rash, abdominal pain, arthritisarthralgia, and glomerulonephritis. Henochschonlein purpura is caused by an abnormal immune system response in which the bodys immune system attacks the bodys own cells and organs. Gastroenterology research practice 2010, article id 597648. Frequently, hsp leads to abdominal pain and intestinal bleeding, renal involvement and joint pain. Jul 24, 2019 henoch schonlein purpura also known as iga vasculitis is a disorder that causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed. Henoch schonlein purpura hsp is a disease involving inflammation of small blood vessels. It predominantly affects the skin, joints, gastrointestinal. Henochschonlein purpura hsp, also known as iga vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. Dec 10, 2018 the vast majority of people with henoch schonlein purpura hsp recover on their own within several weeks. Henoch schonlein purpura hsp is the most common vasculitis of childhood with an incidence of 1418100 000 children per year.
The inflammation causes blood vessels in the skin, intestines. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Henochschonlein purpura symptoms and causes mayo clinic. Gastrointestinal manifestations of henoch schonlein purpura. Henoch schonlein purpura hsp is the most common vasculitis of childhood and affects the small vessels. Henochschonlein purpura symptoms, diagnosis and treatment. Therapy for children with henochschonlein purpura nephritis. Vasculitis is a general term that refers to the inflammation irritation and swelling of. Hsp is most common in younger pts clinical red maculopapules on legs and buttocks. Henochschonlein purpura definition of henochschonlein. Henoch schonlein purpura, nephritis, therapy, children introduction henoch schonlein purpura hsp is an immunologically mediated disease associating purpura plus urticaria, characteristically affecting lower limbs, buttocks, and elbows.
Henoch schonlein purpura hsp is the most common form of acute vasculitis primarily affecting children. Usually, the immune system makes antibodies, or proteins, to protect the body from foreign substances such as bacteria or viruses. Neurologic manifestations of schonlein henoch purpura. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain. Hypersensitivity vasculitis and henochschonlein purpura.
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